It is a very individual matter: some people will feel their effect almost immediately, while others will feel it in a week or so. We recommend you start with 2 capsules, twice a day and then determine which dose works better for you, depending on your own sensitivity. A single capsule a day will be too low to most people and 10 is too much. Generally speaking, it is advisable to take an herb for at least one month to gauge its effects.